Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcγRI

Monocyte-derived, fibroblast-like cells, called fibrocytes, participate in wound-healing and the formation of fibrotic lesions. Aggregated or cross-linked IgG are key effectors in infections, autoimmune diseases, anaphylaxis, and immunotherapy. Cells, including monocytes and fibrocytes, bind IgG usi...

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Bibliographic Details
Main Authors: Pilling, Darrell, Crawford, Jeffrey R., Verbeek, J. Sjef, Gomer, Richard H.
Format: Artigo
Language:Inglês
Published: Society for Leukocyte Biology 2014
Subjects:
Inflammation, Extracellular Mediators, & Effector Molecules
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101091/
https://ncbi.nlm.nih.gov/pubmed/24752483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3AB0913-490RR
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