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FcγRI mediates serum amyloid P inhibition of fibrocyte differentiation

Fibrotic diseases, such as cardiac and pulmonary fibrosis, have a poor prognosis with no FDA approved therapies. Monocyte-derived, fibroblast-like cells, called fibrocytes, participate in the formation of fibrotic lesions. The conserved pentraxin protein SAP inhibits fibrocyte differentiation in cel...

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Bibliografische gegevens
Hoofdauteurs: Crawford, Jeffrey R., Pilling, Darrell, Gomer, Richard H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Leukocyte Biology 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441318/
https://ncbi.nlm.nih.gov/pubmed/22493081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0112033
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