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CGX1037 is a novel PKC isoform delta selective inhibitor in platelets

Platelets upon activation change their shape, aggregate and secrete alpha and dense granule contents among which ADP acts as a feedback activator. Different Protein Kinase C (PKC) isoforms have specific non-redundant roles in mediating platelet responses including secretion and thrombus formation. M...

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Bibliografiske detaljer
Main Authors: BHAVANASI, DHEERAJ, KOSTYAK, JOHN C., SWINDLE, JOHN, KILPATRICK, LAURIE E., KUNAPULI, SATYA P.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101062/
https://ncbi.nlm.nih.gov/pubmed/24433221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09537104.2013.868877
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