Transcriptomes and shRNA Suppressors in a TP53 Allele-specific Model of Early-onset Colon Cancer in African Americans

African Americans are disproportionately affected by early-onset, high-grade malignancies. A fraction of this cancer health disparity can be explained by genetic differences between individuals of African or European descent. Here the wild-type Pro/Pro genotype at the TP53Pro72Arg (P72R) polymorphis...

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Main Authors: Weige, Charles C., Birtwistle, Marc R., Mallick, Himel, Yi, Nengjun, Berrong, Zuzana, Cloessner, Emily, Duff, Keely, Tidwell, Josephine, Clendenning, Megan, Wilkerson, Brent, Farrell, Christopher, Bunz, Fred, Ji, Hao, Shtutman, Michael, Creek, Kim E., Banister, Carolyn E., Buckhaults, Phillip J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101030/
https://ncbi.nlm.nih.gov/pubmed/24743655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0286-T
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