Focal adhesion kinase: An alternative focus for anti-angiogenesis therapy in ovarian cancer

This investigation describes the clinical significance of phosphorylated focal adhesion kinase (FAK) at the major activating tyrosine site (Y397) in epithelial ovarian cancer (EOC) cells and tumor-associated endothelial cells. FAK gene amplification as a mechanism for FAK overexpression and the effe...

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書誌詳細
主要な著者: Stone, Rebecca L, Baggerly, Keith A, Armaiz-Pena, Guillermo N, Kang, Yu, Sanguino, Angela M, Thanapprapasr, Duangmani, Dalton, Heather J, Bottsford-Miller, Justin, Zand, Behrouz, Akbani, Rehan, Diao, Lixia, Nick, Alpa M, DeGeest, Koen, Lopez-Berestein, Gabriel, Coleman, Robert L, Lutgendorf, Susan, Sood, Anil K
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2014
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100993/
https://ncbi.nlm.nih.gov/pubmed/24755674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28882
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