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Menin Epigenetically Represses Hedgehog signaling in MEN1 Tumor Syndrome
Multiple endocrine neoplasia type 1 (MEN1) is an inherited tumor syndrome that includes susceptibility to pancreatic islet tumors. This syndrome results from mutations in the MEN1 gene, encoding menin. Menin acts as an oncogenic co-factor for MLL-fusion protein-mediated histone H3 lysine 4 methylati...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4100916/ https://ncbi.nlm.nih.gov/pubmed/23580576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3158 |
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