Menin Epigenetically Represses Hedgehog signaling in MEN1 Tumor Syndrome

Multiple endocrine neoplasia type 1 (MEN1) is an inherited tumor syndrome that includes susceptibility to pancreatic islet tumors. This syndrome results from mutations in the MEN1 gene, encoding menin. Menin acts as an oncogenic co-factor for MLL-fusion protein-mediated histone H3 lysine 4 methylati...

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Библиографические подробности
Главные авторы: Gurung, Buddha, Feng, Zijie, Iwamoto, Daniel V., Thiel, Austin, Jin, Guanghui, Fan, Chen-Min, Ng, Jessica M., Curran, Tom, Hua, Xianxin
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100916/
https://ncbi.nlm.nih.gov/pubmed/23580576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3158
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