Stiffening-Induced High Pulsatility Flow Activates Endothelial Inflammation via a TLR2/NF-κB Pathway

Stiffening of large arteries is increasingly used as an independent predictor of risk and therapeutic outcome for small artery dysfunction in many diseases including pulmonary hypertension. The molecular mechanisms mediating downstream vascular cell responses to large artery stiffening remain unclea...

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Bibliographic Details
Main Authors: Tan, Yan, Tseng, Pi-Ou, Wang, Daren, Zhang, Hui, Hunter, Kendall, Hertzberg, Jean, Stenmark, Kurt R., Tan, Wei
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100881/
https://ncbi.nlm.nih.gov/pubmed/25029271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102195
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