Stiffening-Induced High Pulsatility Flow Activates Endothelial Inflammation via a TLR2/NF-κB Pathway

Stiffening of large arteries is increasingly used as an independent predictor of risk and therapeutic outcome for small artery dysfunction in many diseases including pulmonary hypertension. The molecular mechanisms mediating downstream vascular cell responses to large artery stiffening remain unclea...

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Bibliographische Detailangaben
Hauptverfasser: Tan, Yan, Tseng, Pi-Ou, Wang, Daren, Zhang, Hui, Hunter, Kendall, Hertzberg, Jean, Stenmark, Kurt R., Tan, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100881/
https://ncbi.nlm.nih.gov/pubmed/25029271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102195
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