Stiffening-Induced High Pulsatility Flow Activates Endothelial Inflammation via a TLR2/NF-κB Pathway

Stiffening of large arteries is increasingly used as an independent predictor of risk and therapeutic outcome for small artery dysfunction in many diseases including pulmonary hypertension. The molecular mechanisms mediating downstream vascular cell responses to large artery stiffening remain unclea...

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Main Authors: Tan, Yan, Tseng, Pi-Ou, Wang, Daren, Zhang, Hui, Hunter, Kendall, Hertzberg, Jean, Stenmark, Kurt R., Tan, Wei
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100881/
https://ncbi.nlm.nih.gov/pubmed/25029271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102195
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