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A zanamivir dimer with prophylactic and enhanced therapeutic activity against influenza viruses
OBJECTIVES: Emerging drug resistance to antiviral therapies is an increasing challenge for the treatment of influenza virus infections. One new antiviral compound, BTA938, a dimeric derivative of the viral neuraminidase inhibitor zanamivir, contains a 14-carbon linker bridging two zanamivir moieties...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4100710/ https://ncbi.nlm.nih.gov/pubmed/24777908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku127 |
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