CLINICAL UTILITY OF IMMUNOHISTOCHEMISTRY FOR THE DETECTION OF THE BRAF V600E MUTATION IN PAPILLARY THYROID CARCINOMA

BACKGROUND: BRAF V600E mutation is the most common genetic alteration in papillary thyroid cancer (PTC). We utilized a mutation-specific antibody for immunohistochemical (IHC) detection of the BRAF V600E mutation and correlated expression with clinicopathological features. The study was designed to...

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Main Authors: Zagzag, Jonathan, Pollack, Aron, Dultz, Linda, Dhar, Shumon, Ogilvie, Jennifer B., Heller, Keith S., Deng, Fang-Ming, Patel, Kepal N.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100700/
https://ncbi.nlm.nih.gov/pubmed/23931769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2013.06.020
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