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Immunohistochemistry is highly sensitive and specific for detecting the BRAF V600E mutation in papillary thyroid carcinoma

The V600E mutation in the B-type Raf kinase (BRAF) gene is a common genetic change in cases of papillary thyroid carcinoma (PTC) that appears to play a key role in the development and progression of this disease. We sought to assess the sensitivity and specificity of immunohistochemical detection of...

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Publicat a:Int J Clin Exp Pathol
Autors principals: Sun, Jian, Zhang, Jing, Lu, Junliang, Gao, Jie, Lu, Tao, Ren, Xinyu, Duan, Huanli, Liang, Zhiyong
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713632/
https://ncbi.nlm.nih.gov/pubmed/26823846
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