Maternal obesity down-regulates microRNA (miRNA) let-7g expression, a possible mechanism for enhanced adipogenesis during ovine fetal skeletal muscle development

BACKGROUND: Obesity in women of childbearing age is increasing at an alarming rate. Growing evidence shows that maternal obesity induces detrimental effects on offspring health including pre-disposition to obesity. We have shown that maternal obesity increases fetal intramuscular adipogenesis at mid...

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Huvudupphovsmän: Yan, Xu, Huang, Yan, Zhao, Jun-Xing, Rogers, Carl J., Zhu, Mei-Jun, Ford, Stephen P., Nathanielsz, Peter W., Du, Min
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100693/
https://ncbi.nlm.nih.gov/pubmed/22614057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2012.69
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