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Enhanced transforming growth factor-β signaling and fibrogenesis in ovine fetal skeletal muscle of obese dams at late gestation

Maternal obesity (MO) is increasing at an alarming rate. The objective of this study was to evaluate the effect of MO on fibrogenesis in fetal skeletal muscle during maturation in late gestation. Nonpregnant ewes were assigned to a control diet (Con; fed 100% of NRC nutrient recommendations, n = 6)...

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Bibliographic Details
Main Authors: Huang, Yan, Yan, Xu, Zhu, Mei J., McCormick, Richard J., Ford, Stephen P., Nathanielsz, Peter W., Du, Min
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886526/
https://ncbi.nlm.nih.gov/pubmed/20371734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00015.2010
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