Attenuation of dextran sodium sulphate induced colitis in matrix metalloproteinase-9 deficient mice

AIM: To study whether matrix metalloproteinase-9 (MMP-9) is a key factor in epithelial damage in the dextran sodium sulphate (DSS) model of colitis in mice. METHODS: MMP-9-deficient and wild-type (wt) mice were given 5% DSS in drinking water for 5 d followed by recovery up to 7 d. On d 5 and 12 afte...

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Autores principales: Santana, Alfredo, Medina, Carlos, Paz-Cabrera, Maria Cristina, Díaz-Gonzalez, Federico, Farré, Esther, Salas, Antonio, Radomski, Marek W, Quintero, Enrique
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Co., Limited 2006
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100636/
https://ncbi.nlm.nih.gov/pubmed/17072979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i40.6464
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