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Replication-coupled DNA Interstrand Crosslink repair in Xenopus egg extracts

Interstrand crosslinks (ICL) are one of the most hazardous types of DNA damage as they form a roadblock to all processes that involve strand separation. Repair of these lesions involves several different DNA repair pathways but the molecular mechanism is unclear. Here we describe a system that allow...

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Autors principals: Knipscheer, Puck, Räschle, Markus, Schärer, Orlando D., Walter, Johannes C.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100613/
https://ncbi.nlm.nih.gov/pubmed/22941607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-998-3_16
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