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Spontaneous activation of RNA-sensing pathways in autoimmune disease

Multiple intracellular RNA sensing innate immune pathways have been linked to autoimmune disease. RNA-related ligands taken up by the endocytic pathway activate TLRs, and affect primarily immune cells. This type of activation is enhanced by nucleic acid-specific antibodies and induces an inflammator...

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Sonraí Bibleagrafaíochta
Main Authors: Crampton, Steve P, Bolland, Silvia
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100591/
https://ncbi.nlm.nih.gov/pubmed/24455767
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