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Immunologic Applications of Conditional Gene Modification Technology in the Mouse

Since the success of homologous recombination in altering mouse genome and the discovery of Cre-loxP system, the combination of these two breakthroughs has created important applications for studying the immune system in the mouse. Here, we briefly summarize the general principles of this technology...

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Detalhes bibliográficos
Main Authors: Sharma, Suveena, Zhu, Jinfang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100247/
https://ncbi.nlm.nih.gov/pubmed/24700321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142735.im1034s105
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