Urinary concentrating defect in mice with selective deletion of phloretin-sensitive urea transporters in the renal collecting duct

To investigate the role of inner medullary collecting duct (IMCD) urea transporters in the renal concentrating mechanism, we deleted 3 kb of the UT-A urea transporter gene containing a single 140-bp exon (exon 10). Deletion of this segment selectively disrupted expression of the two known IMCD isofo...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Fenton, Robert A., Chou, Chung-Lin, Stewart, Gavin S., Smith, Craig P., Knepper, Mark A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2004
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC409942/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15123796/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401704101
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