Chlamydial histone-DNA interactions are disrupted by a metabolite in the methylerythritol phosphate pathway of isoprenoid biosynthesis

The chlamydial developmental cycle is characterized by an intracellular replicative form, termed the reticulate body, and an extracellular form called the elementary body. Elementary bodies are characterized by a condensed chromatin, which is maintained by a histone H1-like protein, Hc1. Differentia...

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Autores principales: Grieshaber, Nicole A., Fischer, Elizabeth R., Mead, David J., Dooley, Cheryl A., Hackstadt, Ted
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC409939/
https://ncbi.nlm.nih.gov/pubmed/15123794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400754101
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