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Chlamydial histone-DNA interactions are disrupted by a metabolite in the methylerythritol phosphate pathway of isoprenoid biosynthesis

The chlamydial developmental cycle is characterized by an intracellular replicative form, termed the reticulate body, and an extracellular form called the elementary body. Elementary bodies are characterized by a condensed chromatin, which is maintained by a histone H1-like protein, Hc1. Differentia...

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Autori principali: Grieshaber, Nicole A., Fischer, Elizabeth R., Mead, David J., Dooley, Cheryl A., Hackstadt, Ted
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC409939/
https://ncbi.nlm.nih.gov/pubmed/15123794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400754101
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