The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry

Entry of herpes simplex virus (HSV) 1 into cells requires the interaction of HSV gD with herpesvirus entry mediator or nectin1 receptors, and fusion with cell membrane mediated by the fusion glycoproteins gB, gH, and gL. We report that the gD ectodomain in soluble form (amino acids 1-305) was suffic...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Cocchi, Francesca, Fusco, Daniela, Menotti, Laura, Gianni, Tatiana, Eisenberg, Roselyn J., Cohen, Gary H., Campadelli-Fiume, Gabriella
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC409938/
https://ncbi.nlm.nih.gov/pubmed/15123804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401883101
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