The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry

Entry of herpes simplex virus (HSV) 1 into cells requires the interaction of HSV gD with herpesvirus entry mediator or nectin1 receptors, and fusion with cell membrane mediated by the fusion glycoproteins gB, gH, and gL. We report that the gD ectodomain in soluble form (amino acids 1-305) was suffic...

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Detalhes bibliográficos
Main Authors: Cocchi, Francesca, Fusco, Daniela, Menotti, Laura, Gianni, Tatiana, Eisenberg, Roselyn J., Cohen, Gary H., Campadelli-Fiume, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC409938/
https://ncbi.nlm.nih.gov/pubmed/15123804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401883101
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