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The Bromodomain: From Epigenome Reader to Druggable Target

Lysine acetylation is a fundamental post-translational modification that plays an important role in control of gene transcription in chromatin in an ordered fashion. The bromodomain, the conserved structural module present in transcription-associated proteins, functions exclusively to recognize acet...

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Detalhes bibliográficos
Main Authors: Sanchez, Roberto, Meslamani, Jamel, Zhou, Ming-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099289/
https://ncbi.nlm.nih.gov/pubmed/24686119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.03.011
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