Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP)

BACKGROUND: Homologous recombination repair (HRR) pathway deficiencies have significant implications for cancer predisposition and treatment strategies. Improved quantitative methods for functionally characterizing these deficiencies are required to accurately identify patients at risk of developing...

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Main Authors: Rosen, David B, Leung, Ling Y, Louie, Brent, Cordeiro, James A, Conroy, Andrew, Shapira, Iuliana, Fields, Scott Z, Cesano, Alessandra, Hawtin, Rachael E
格式: Artigo
語言:Inglês
出版: BioMed Central 2014
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099151/
https://ncbi.nlm.nih.gov/pubmed/24965603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-184
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