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The C-terminal domain of DNA gyrase A adopts a DNA-bending β-pinwheel fold

DNA gyrase is unique among enzymes for its ability to actively introduce negative supercoils into DNA. This function is mediated in part by the C-terminal domain of its A subunit (GyrA CTD). Here, we report the crystal structure of this ≈35-kDa domain determined to 1.75-Å resolution. The GyrA CTD un...

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Detalhes bibliográficos
Main Authors: Corbett, Kevin D., Shultzaberger, Ryan K., Berger, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC409912/
https://ncbi.nlm.nih.gov/pubmed/15123801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401595101
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