ERCC1 Cys8092Ala and XRCC1 Arg399Gln Polymorphisms Predict Progression-Free Survival after Curative Radiotherapy for Nasopharyngeal Carcinoma

BACKGROUND: Single nucleotide polymorphisms (SNPs) in DNA repair genes can alter gene expression and activity and affect response to cancer treatment and, correspondingly, survival. The present study was designed to evaluate the utility of the XRCC1 Arg399Gln and ERCC1 Cys8092Ala SNPs, measured in p...

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Autori principali: Jin, Hekun, Xie, Xiaoxue, Wang, Hui, Hu, Jun, Liu, Feng, Liu, Zhigang, Zhou, Jumei, Zhang, Yingying, Xi, Xuping, Hu, Bingqiang, Liao, Yuping, Tang, Jingtian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099069/
https://ncbi.nlm.nih.gov/pubmed/25025378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101256
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