ERCC1 Cys8092Ala and XRCC1 Arg399Gln Polymorphisms Predict Progression-Free Survival after Curative Radiotherapy for Nasopharyngeal Carcinoma

BACKGROUND: Single nucleotide polymorphisms (SNPs) in DNA repair genes can alter gene expression and activity and affect response to cancer treatment and, correspondingly, survival. The present study was designed to evaluate the utility of the XRCC1 Arg399Gln and ERCC1 Cys8092Ala SNPs, measured in p...

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Detalhes bibliográficos
Main Authors: Jin, Hekun, Xie, Xiaoxue, Wang, Hui, Hu, Jun, Liu, Feng, Liu, Zhigang, Zhou, Jumei, Zhang, Yingying, Xi, Xuping, Hu, Bingqiang, Liao, Yuping, Tang, Jingtian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099069/
https://ncbi.nlm.nih.gov/pubmed/25025378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101256
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