Antibodies Specific for Carbamylated Proteins Precede the Onset of Clinical Symptoms in Mice with Collagen Induced Arthritis

OBJECTIVE: The immune response to post-translationally modified antigens is a key characteristic of rheumatoid arthritis. Carbamylation is such a posttranslational modification. Recently, we demonstrated that autoantibodies recognizing carbamylated proteins are present in sera of rheumatoid arthriti...

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Main Authors: Stoop, Jeroen N., Liu, Bi-Sheng, Shi, Jing, Jansen, Diahann T. S. L., Hegen, Martin, Huizinga, Tom W. J., Trouw, Leendert A., Toes, René E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099068/
https://ncbi.nlm.nih.gov/pubmed/25025869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102163
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