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Structural basis of silencing: Sir3 BAH domain in complex with a nucleosome at 3.0 Å resolution
Gene silencing is essential for regulating cell fate in eukaryotes. Altered chromatin architectures contribute to maintaining the silenced state in a variety of species. The silent information regulator (SIR) proteins regulate mating type in S. cerevisiae. One of these proteins, Sir3, interacts dire...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4098850/ https://ncbi.nlm.nih.gov/pubmed/22096199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1210915 |
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