BLX‐1002 restores glucose sensitivity and enhances insulin secretion stimulated by GLP‐1 and sulfonylurea in type 2 diabetic pancreatic islets

BLX‐1002 is a novel thiazolidinedione with no peroxisome proliferator‐activated receptor (PPAR) activity that has been shown to improve glycemia in type 2 diabetes without weight gain. We previously found that BLX‐1002 selectively augments glucose‐sensitive (but not basal) insulin secretion in norma...

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Main Authors: Zhang, Qimin, Zhang, Fan, Sjöholm, Åke
Formáid: Artigo
Teanga:Inglês
Foilsithe: Wiley Periodicals, Inc. 2014
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098742/
https://ncbi.nlm.nih.gov/pubmed/24872354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12014
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