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Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming

SUMMARY: During Mycobacterium tuberculosis and other respiratory infections, optimal T cell activation requires pathogen transport from the lung to a local draining lymph node (LN). However, the infected inflammatory monocyte-derived dendritic cells (DCs) that transport M. tuberculosis to the local...

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Main Authors: Srivastava, Smita, Ernst, Joel D.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098643/
https://ncbi.nlm.nih.gov/pubmed/24922576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.05.007
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