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Antigen export reduces antigen presentation and limits T cell control of M. tuberculosis
Persistence of Mycobacterium tuberculosis results from bacterial strategies that manipulate host adaptive immune responses. Infected dendritic cells (DCs) transport M. tuberculosis to local lymph nodes but activate CD4 T cells poorly, suggesting bacterial manipulation of antigen presentation. Howeve...
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| Publicado no: | Cell Host Microbe |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4715867/ https://ncbi.nlm.nih.gov/pubmed/26764596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.12.003 |
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