Lack of chemokine receptor CCR1 enhances Th1 responses and glomerular injury during nephrotoxic nephritis

During the development of nephrotoxic nephritis (NTN) in the mouse, we find that a variety of chemokines and chemokine receptors are induced: CCR1 (RANTES, MIP-1α), CCR2 (MCP-1), CCR5 (RANTES, MIP-1α, MIP-1β), CXCR2 (MIP-2), and CXCR3 (IP-10). Their timing of expression indicated that CXCR2 and CCR1...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Topham, Peter S., Csizmadia, Vilmos, Soler, Dulce, Hines, Dawn, Gerard, Craig J., Salant, David J., Hancock, Wayne W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC409862/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10587518/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI7707
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