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Targeting of the chemokine receptor CCR1 suppresses development of acute and chronic cardiac allograft rejection

Although mononuclear cell infiltration is a hallmark of cellular rejection of a vascularized allograft, efforts to inhibit rejection by blocking leukocyte-endothelial cell adhesion have proved largely unsuccessful, perhaps in part because of persistent generation of chemokines within rejecting graft...

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Detalhes bibliográficos
Main Authors: Gao, Wei, Topham, Peter S., King, Jennifer A., Smiley, Stephen T., Csizmadia, Vilmos, Lu, Bao, Gerard, Craig J., Hancock, Wayne W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC382589/
https://ncbi.nlm.nih.gov/pubmed/10619859
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