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Targeted deletion of CX(3)CR1 reveals a role for fractalkine in cardiac allograft rejection

Fractalkine (Fk) is a structurally unusual member of the chemokine family. To determine its role in vivo, we generated mice with a targeted disruption of CX(3)CR1, the receptor for Fk. CX(3)CR1(–/–) mice were phenotypically indistinguishable from wild-type mice in a pathogen-free environment. In res...

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Detalhes bibliográficos
Main Authors: Haskell, Christopher A., Hancock, Wayne W., Salant, David J., Gao, Wei, Csizmadia, Vilmos, Peters, Wendy, Faia, Kerrie, Fituri, Omar, Rottman, James B., Charo, Israel F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC209384/
https://ncbi.nlm.nih.gov/pubmed/11544273
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