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A murine model of hereditary hemorrhagic telangiectasia

Endoglin (CD105), an accessory protein of the TGF-β receptor superfamily, is highly expressed on endothelial cells. Hereditary hemorrhagic telangiectasia type 1 (HHT1) is associated with mutations in the Endoglin gene, leading to haploinsufficiency. To generate a disease model and ascertain the role...

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Hlavní autoři: Bourdeau, Annie, Dumont, Daniel J., Letarte, Michelle
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC409846/
https://ncbi.nlm.nih.gov/pubmed/10562296
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