A PDZ-interacting domain in CFTR is an apical membrane polarization signal
Polarization of the cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP-activated chloride channel, to the apical plasma membrane of epithelial cells is critical for vectorial transport of chloride in a variety of epithelia, including the airway, pancreas, intestine, and kidney. Howev...
Guardat en:
| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC409842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10562297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI7453 |
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