The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow

The chemokine SDF-1 plays a central role in the repopulation of the bone marrow (BM) by circulating CD34(+) progenitors, but the mechanisms of its action remain obscure. To extravasate to target tissue, a blood-borne cell must arrest firmly on vascular endothelium. Murine hematopoietic progenitors w...

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Main Authors: Peled, Amnon, Grabovsky, Valentin, Habler, Liliana, Sandbank, Judith, Arenzana-Seisdedos, Frenando, Petit, Isabelle, Ben-Hur, Herzl, Lapidot, Tsvee, Alon, Ronen
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1999
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC409822/
https://ncbi.nlm.nih.gov/pubmed/10545519
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