The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow

The chemokine SDF-1 plays a central role in the repopulation of the bone marrow (BM) by circulating CD34(+) progenitors, but the mechanisms of its action remain obscure. To extravasate to target tissue, a blood-borne cell must arrest firmly on vascular endothelium. Murine hematopoietic progenitors w...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Peled, Amnon, Grabovsky, Valentin, Habler, Liliana, Sandbank, Judith, Arenzana-Seisdedos, Frenando, Petit, Isabelle, Ben-Hur, Herzl, Lapidot, Tsvee, Alon, Ronen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1999
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC409822/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10545519/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI7615
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