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Atypical PKC-ζ regulates SDF-1–mediated migration and development of human CD34(+) progenitor cells
The chemokine stromal cell–derived factor–1 (SDF-1) and its receptor, CXCR4, play a major role in migration, retention, and development of hematopoietic progenitors in the bone marrow. We report the direct involvement of atypical PKC-ζ in SDF-1 signaling in immature human CD34(+)-enriched cells and...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC539190/ https://ncbi.nlm.nih.gov/pubmed/15630457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200521773 |
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