Functional Prostacyclin Synthase Promoter Polymorphisms. Impact in Pulmonary Arterial Hypertension

Rationale: Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pulmonary artery pressure, vascular remodeling, and ultimately right ventricular heart failure. PAH can have a genetic component (heritable PAH), most often through mutations of bone morphogenetic pro...

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Main Authors: Stearman, Robert S., Cornelius, Amber R., Lu, Xiao, Conklin, David S., Del Rosario, Mark J., Lowe, Anita M., Elos, Mihret T., Fettig, Lynsey M., Wong, Randall E., Hara, Naoko, Cogan, Joy D., Phillips, John A., Taylor, Matthew R., Graham, Brian B., Tuder, Rubin M., Loyd, James E., Geraci, Mark W.
格式: Artigo
語言:Inglês
出版: American Thoracic Society 2014
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098107/
https://ncbi.nlm.nih.gov/pubmed/24605778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201309-1697OC
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