Functional Prostacyclin Synthase Promoter Polymorphisms. Impact in Pulmonary Arterial Hypertension

Rationale: Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pulmonary artery pressure, vascular remodeling, and ultimately right ventricular heart failure. PAH can have a genetic component (heritable PAH), most often through mutations of bone morphogenetic pro...

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Main Authors: Stearman, Robert S., Cornelius, Amber R., Lu, Xiao, Conklin, David S., Del Rosario, Mark J., Lowe, Anita M., Elos, Mihret T., Fettig, Lynsey M., Wong, Randall E., Hara, Naoko, Cogan, Joy D., Phillips, John A., Taylor, Matthew R., Graham, Brian B., Tuder, Rubin M., Loyd, James E., Geraci, Mark W.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2014
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098107/
https://ncbi.nlm.nih.gov/pubmed/24605778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201309-1697OC
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