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The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and APOE genes
INTRODUCTION: We investigated the TOMM40-APOE genomic region that has been associated with the risk and age of onset of late-onset Alzheimer's disease (LOAD) to determine if a highly polymorphic, intronic polyT within this region (rs10524523, hereafter 523) affects expression of the APOE and TO...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2014
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4098029/ https://ncbi.nlm.nih.gov/pubmed/24439168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2013.08.280 |
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