Replication of Many Human Viruses Is Refractory to Inhibition by Endogenous Cellular MicroRNAs

The issue of whether viruses are subject to restriction by endogenous microRNAs (miRNAs) and/or by virus-induced small interfering RNAs (siRNAs) in infected human somatic cells has been controversial. Here, we address this question in two ways. First, using deep sequencing, we demonstrate that infec...

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Detalhes bibliográficos
Main Authors: Bogerd, Hal P., Skalsky, Rebecca L., Kennedy, Edward M., Furuse, Yuki, Whisnant, Adam W., Flores, Omar, Schultz, Kimberly L. W., Putnam, Nicole, Barrows, Nicholas J., Sherry, Barbara, Scholle, Frank, Garcia-Blanco, Mariano A., Griffin, Diane E., Cullen, Bryan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097787/
https://ncbi.nlm.nih.gov/pubmed/24807715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00985-14
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