Analysis of Recombinant H7N9 Wild-Type and Mutant Viruses in Pigs Shows that the Q226L Mutation in HA Is Important for Transmission

The fact that there have been more than 300 human infections with a novel avian H7N9 virus in China indicates that this emerging strain has pandemic potential. Furthermore, many of the H7N9 viruses circulating in animal reservoirs contain putative mammalian signatures in the HA and PB2 genes that ar...

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Main Authors: Liu, Qinfang, Zhou, Bin, Ma, Wenjun, Bawa, Bhupinder, Ma, Jingjiao, Wang, Wei, Lang, Yuekun, Lyoo, Young, Halpin, Rebecca A., Lin, Xudong, Stockwell, Timothy B., Webby, Richard, Wentworth, David E., Richt, Juergen A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097782/
https://ncbi.nlm.nih.gov/pubmed/24807722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00894-14
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