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Development and Clinical Evaluation of sdaA Loop-Mediated Isothermal Amplification Assay for Detection of Mycobacterium tuberculosis with an Approach To Prevent Carryover Contamination

A rapid and sensitive loop-mediated isothermal amplification assay for the sdaA gene of Mycobacterium tuberculosis was developed using a dUTP-uracil-N-glycosylase (dUTP-UNG) strategy to prevent carryover contamination. Evaluation of the assay using clinical specimens (n = 648) showed high specificit...

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Autori principali: Nimesh, Manoj, Joon, Deepali, Varma-Basil, Mandira, Saluja, Daman
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097723/
https://ncbi.nlm.nih.gov/pubmed/24789191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00907-14
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