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14-3-3τ Promotes Breast Cancer Invasion and Metastasis by Inhibiting RhoGDIα

14-3-3τ is frequently overexpressed in breast cancer; however, whether it contributes to breast cancer progression remains undetermined. Here, we identify a critical role for 14-3-3τ in promoting breast cancer metastasis, in part through binding to and inhibition of RhoGDIα, a negative regulator of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xiao, Yang, Lin, Vivian Y., Ke, Shi, Lin, Gregory E., Lin, Fang-Tsyr, Lin, Weei-Chin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097670/
https://ncbi.nlm.nih.gov/pubmed/24820414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00076-14
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