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Binding of the WASP/N-WASP-Interacting Protein WIP to Actin Regulates Focal Adhesion Assembly and Adhesion
The actin cytoskeleton is essential for cell adhesion and migration, functions important for tumor invasion. In addition to binding N-WASP/WASP, WIP binds and stabilizes F-actin. WIP(−/−) fibroblasts were used to test the role of WIP in F-actin function. WIP(−/−) cells had defective focal adhesion (...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4097659/ https://ncbi.nlm.nih.gov/pubmed/24797074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00017-14 |
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