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Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase.

Cyclin B/cdc2 is responsible both for driving cells into mitosis and for activating the ubiquitin-dependent degradation of mitotic cyclins near the end of mitosis, an event required for the completion of mitosis and entry into interphase of the next cell cycle. Previous work with cell-free extracts...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lahav-Baratz, S, Sudakin, V, Ruderman, J V, Hershko, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40973/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568122/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.20.9303
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