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Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase

Destruction of mitotic cyclins by ubiquitin-dependent proteolysis is required for cells to complete mitosis and enter interphase of the next cell cycle. In clam eggs, this process is catalyzed by a cyclin-selective ubiquitin carrier protein, E2-C, and the cyclosome/anaphase promoting complex (APC),...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Townsley, Fiona M., Aristarkhov, Alexander, Beck, Sharon, Hershko, Avram, Ruderman, Joan V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20093/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2362
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